import { ClinicalUseDefinition } from './ClinicalUseDefinition.js';
import { ClinicalUseDefinition_Contraindication_OtherTherapy } from './ClinicalUseDefinition_Contraindication_OtherTherapy.js';
import { CodeableReference } from './CodeableReference.js';
import { Expression } from './Expression.js';
import { Extension } from './Extension.js';
import { ObservationDefinition } from './ObservationDefinition.js';
import { Reference } from './Reference.js';
export interface ClinicalUseDefinition_Contraindication {
    /**
     * @description Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
     * @short Unique id for inter-element referencing
     */
    id?: string;
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Additional content defined by implementations
     */
    extension?: Extension[];
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained andor the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
  
  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Extensions that cannot be ignored even if unrecognized
     */
    modifierExtension?: Extension[];
    /**
     * @description The situation that is being documented as contraindicating against this item.
     * @short The situation that is being documented as contraindicating against this item
     */
    diseaseSymptomProcedure?: CodeableReference<ObservationDefinition>;
    /**
     * @description The status of the disease or symptom for the contraindication, for example "chronic" or "metastatic".
     * @short The status of the disease or symptom for the contraindication
     */
    diseaseStatus?: CodeableReference<ObservationDefinition>;
    /**
     * @description A comorbidity (concurrent condition) or coinfection.
     * @short A comorbidity (concurrent condition) or coinfection
     */
    comorbidity?: CodeableReference<ObservationDefinition>[];
    /**
     * @description The indication which this is a contraidication for.
     * @short The indication which this is a contraidication for
     */
    indication?: Reference<ClinicalUseDefinition>[];
    /**
     * @description An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements.
     * @comment The expression may be inlined or may be a reference to a named expression within a logic library referenced by the library element.
     * @short An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements
     */
    applicability?: Expression;
    /**
     * @backbone Nested BackboneElement: otherTherapy [0..*]
     */
    otherTherapy?: ClinicalUseDefinition_Contraindication_OtherTherapy[];
}
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