import { CodeableConcept } from './CodeableConcept.js';
import { DocumentReference } from './DocumentReference.js';
import { Extension } from './Extension.js';
import { FhirPrimitive } from './FhirPrimitive.js';
import { Reference } from './Reference.js';
import { SubstanceDefinition_Structure_Representation } from './SubstanceDefinition_Structure_Representation.js';
export interface SubstanceDefinition_Structure {
    /**
     * @description Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
     * @short Unique id for inter-element referencing
     */
    id?: string;
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Additional content defined by implementations
     */
    extension?: Extension[];
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained andor the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
  
  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Extensions that cannot be ignored even if unrecognized
     */
    modifierExtension?: Extension[];
    /**
     * @description Stereochemistry type.
     * @short Stereochemistry type
     */
    stereochemistry?: CodeableConcept;
    /**
     * @description Optical activity type.
     * @short Optical activity type
     */
    opticalActivity?: CodeableConcept;
    /**
     * @description An expression which states the number and type of atoms present in a molecule of a substance.
     * @short An expression which states the number and type of atoms present in a molecule of a substance
     */
    molecularFormula?: FhirPrimitive<string>;
    /**
     * @description Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
     * @short Specified per moiety according to the Hill system
     */
    molecularFormulaByMoiety?: FhirPrimitive<string>;
    /**
     * @description The molecular weight or weight range (for proteins, polymers or nucleic acids).
     * @short The molecular weight or weight range
     */
    molecularWeight?: any;
    /**
     * @description The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
     * @short The method used to find the structure e.g. X-ray, NMR
     */
    technique?: CodeableConcept[];
    /**
     * @description The source of information about the structure.
     * @short Source of information for the structure
     */
    sourceDocument?: Reference<DocumentReference>[];
    /**
     * @backbone Nested BackboneElement: representation [0..*]
     */
    representation?: SubstanceDefinition_Structure_Representation[];
}
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