import { CodeableConcept } from './CodeableConcept.js';
import { Extension } from './Extension.js';
import { FhirPrimitive } from './FhirPrimitive.js';
import { Reference } from './Reference.js';
export interface MolecularSequence_Relative_StartingSequence {
    /**
     * @description Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
     * @short Unique id for inter-element referencing
     */
    id?: string;
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Additional content defined by implementations
     */
    extension?: Extension[];
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained andor the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
  
  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Extensions that cannot be ignored even if unrecognized
     */
    modifierExtension?: Extension[];
    /**
     * @description The genome assembly used for starting sequence, e.g. GRCh38.
     * @short The genome assembly used for starting sequence, e.g. GRCh38
     */
    genomeAssembly?: CodeableConcept;
    /**
     * @description Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication ([SO:0000340](http:www.sequenceontology.orgbrowsercurrent_svntermSO:0000340)).
     * @short Chromosome Identifier
     */
    chromosome?: CodeableConcept;
    /**
     * @choice This is part of the sequence[x] choice.
     * @oneOf sequenceCodeableConcept, sequenceString, sequenceReference
     */
    sequenceCodeableConcept?: CodeableConcept;
    /**
     * @choice This is part of the sequence[x] choice.
     * @oneOf sequenceCodeableConcept, sequenceString, sequenceReference
     */
    sequenceString?: FhirPrimitive<string>;
    /**
     * @choice This is part of the sequence[x] choice.
     * @oneOf sequenceCodeableConcept, sequenceString, sequenceReference
     */
    sequenceReference?: Reference;
    /**
     * @description Start position of the window on the starting sequence. This value should honor the rules of the coordinateSystem.
     * @short Start position of the window on the starting sequence
     */
    windowStart?: FhirPrimitive<number>;
    /**
     * @description End position of the window on the starting sequence. This value should honor the rules of the  coordinateSystem.
     * @short End position of the window on the starting sequence
     */
    windowEnd?: FhirPrimitive<number>;
    /**
     * @description A relative reference to a DNA strand based on gene orientation. The strand that contains the open reading frame of the gene is the "sense" strand, and the opposite complementary strand is the "antisense" strand.
     * @short sense | antisense
     */
    orientation?: FhirPrimitive<string>;
    /**
     * @description An absolute reference to a strand. The Watson strand is the strand whose 5'-end is on the short arm of the chromosome, and the Crick strand as the one whose 5'-end is on the long arm.
     * @short watson | crick
     */
    strand?: FhirPrimitive<string>;
}
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