import { ClinicalUseDefinition } from './ClinicalUseDefinition.js';
import { CodeableConcept } from './CodeableConcept.js';
import { Extension } from './Extension.js';
import { FhirPrimitive } from './FhirPrimitive.js';
import { Identifier } from './Identifier.js';
import { Medication } from './Medication.js';
import { MedicationKnowledge_Cost } from './MedicationKnowledge_Cost.js';
import { MedicationKnowledge_Definitional } from './MedicationKnowledge_Definitional.js';
import { MedicationKnowledge_IndicationGuideline } from './MedicationKnowledge_IndicationGuideline.js';
import { MedicationKnowledge_MedicineClassification } from './MedicationKnowledge_MedicineClassification.js';
import { MedicationKnowledge_MonitoringProgram } from './MedicationKnowledge_MonitoringProgram.js';
import { MedicationKnowledge_Monograph } from './MedicationKnowledge_Monograph.js';
import { MedicationKnowledge_Packaging } from './MedicationKnowledge_Packaging.js';
import { MedicationKnowledge_Regulatory } from './MedicationKnowledge_Regulatory.js';
import { MedicationKnowledge_RelatedMedicationKnowledge } from './MedicationKnowledge_RelatedMedicationKnowledge.js';
import { MedicationKnowledge_StorageGuideline } from './MedicationKnowledge_StorageGuideline.js';
import { Meta } from './Meta.js';
import { Narrative } from './Narrative.js';
import { Organization } from './Organization.js';
import { Reference } from './Reference.js';
import { Resource } from './Resource.js';
export interface MedicationKnowledge {
    /**
     * @description The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.
     * @comment Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case.
     * @short Logical id of this artifact
     */
    id?: string;
    /**
     * @description The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.
     * @short Metadata about the resource
     */
    meta?: Meta;
    /**
     * @description A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.
     * @comment Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers andor specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.
     * @short A set of rules under which this content was created
     */
    implicitRules?: FhirPrimitive<string>;
    /**
     * @description The base language in which the resource is written.
     * @comment Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).
     * @short Language of the resource content
     */
    language?: FhirPrimitive<string>;
    /**
     * @description A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.
     * @comment Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.
     * @short Text summary of the resource, for human interpretation
     */
    text?: Narrative;
    /**
     * @description These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides contextmeaning.
     * @comment This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.
     * @short Contained, inline Resources
     */
    contained?: Resource[];
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Additional content defined by implementations
     */
    extension?: Extension[];
    /**
     * @description May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it andor the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
  
  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
     * @comment There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
     * @short Extensions that cannot be ignored
     */
    modifierExtension?: Extension[];
    /**
     * @description Business identifier for this medication.
     * @comment This is a business identifier, not a resource identifier (see discussion).
     * @short Business identifier for this medication
     */
    identifier?: Identifier[];
    /**
     * @description A code that specifies this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.
     * @comment Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true.  As described in the coding datatype: "A coding may be marked as a "userSelected" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).
     * @short Code that identifies this medication
     */
    code?: CodeableConcept;
    /**
     * @description A code to indicate if the medication referred to by this MedicationKnowledge is in active use within the drug database or inventory system. The status refers to the validity about the information of the medication and not to its medicinal properties.
     * @comment This status is intended to identify if the medication in a local system is in active use within a drug database or inventory.  For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status.  At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error".   This status is not intended to specify if a medication is part of a particular formulary.  It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.
     * @short active | entered-in-error | inactive
     */
    status?: FhirPrimitive<string>;
    /**
     * @description The creator or owner of the knowledge or information about the medication.
     * @short Creator or owner of the knowledge or information about the medication
     */
    author?: Reference<Organization>;
    /**
     * @description Lists the jurisdictions that this medication knowledge was written for.
     * @comment The codes could have varying granularity from a country or group of countries down to a specific district.
     * @short Codes that identify the different jurisdictions for which the information of this resource was created
     */
    intendedJurisdiction?: CodeableConcept[];
    /**
     * @description All of the names for a medication, for example, the name(s) given to a medication in different countries.  For example, acetaminophen and paracetamol or salbutamol and albuterol.
     * @short A name associated with the medication being described
     */
    name?: FhirPrimitive<string>[];
    /**
     * @backbone Nested BackboneElement: relatedMedicationKnowledge [0..*]
     */
    relatedMedicationKnowledge?: MedicationKnowledge_RelatedMedicationKnowledge[];
    /**
     * @description Links to associated medications that could be prescribed, dispensed or administered.
     * @short The set of medication resources that are associated with this medication
     */
    associatedMedication?: Reference<Medication>[];
    /**
     * @description Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).
     * @short Category of the medication or product
     */
    productType?: CodeableConcept[];
    /**
     * @backbone Nested BackboneElement: monograph [0..*]
     */
    monograph?: MedicationKnowledge_Monograph[];
    /**
     * @description The instructions for preparing the medication.
     * @short The instructions for preparing the medication
     */
    preparationInstruction?: FhirPrimitive<string>;
    /**
     * @backbone Nested BackboneElement: cost [0..*]
     */
    cost?: MedicationKnowledge_Cost[];
    /**
     * @backbone Nested BackboneElement: monitoringProgram [0..*]
     */
    monitoringProgram?: MedicationKnowledge_MonitoringProgram[];
    /**
     * @backbone Nested BackboneElement: indicationGuideline [0..*]
     */
    indicationGuideline?: MedicationKnowledge_IndicationGuideline[];
    /**
     * @backbone Nested BackboneElement: medicineClassification [0..*]
     */
    medicineClassification?: MedicationKnowledge_MedicineClassification[];
    /**
     * @backbone Nested BackboneElement: packaging [0..*]
     */
    packaging?: MedicationKnowledge_Packaging[];
    /**
     * @description Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).
     * @short Potential clinical issue with or between medication(s)
     */
    clinicalUseIssue?: Reference<ClinicalUseDefinition>[];
    /**
     * @backbone Nested BackboneElement: storageGuideline [0..*]
     */
    storageGuideline?: MedicationKnowledge_StorageGuideline[];
    /**
     * @backbone Nested BackboneElement: regulatory [0..*]
     */
    regulatory?: MedicationKnowledge_Regulatory[];
    /**
     * @backbone Nested BackboneElement: definitional [0..1]
     */
    definitional?: MedicationKnowledge_Definitional;
    /**
     * @const Auto-injected fixed value: MedicationKnowledge
     */
    resourceType: "MedicationKnowledge";
}
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