To add an interaction: Click on interaction type; then click on small circle on source node and release on target node
To add a node into a container (family, complex, compartment or process): Drag the node into its container node or select nodes to be contained and right click on container node and choose "Add Selected Into This"
To delete nodes/interactions: Select and perform Edit > Delete Selected
To overlay experiment data: Select Alteration % > Load From cBioPortal...